Since 2005, BIOMET has developed expertise in metabolomics and lipidomics by high resolution mass spectrometry, in the field of:
- Human health
- Environment and agronomy
BIOMET conducted the largest cross-platform validation test for untargeted metabolomics, the METABORING initiative (free access, doi: 10.1007/s11306-014-0740-0).
BIOMET is ranked in the top 18% of the most publishing structures in the field of metabolomics (source Scholar).
BIOMET has developed a methodology allowing the analysis of more than 830 metabolites and 400-750 types of lipids, with a know-how for statistical analysis and biological interpretation.
BIOMET is also an expert in multi-scale analysis, capable of assembling data sets of different origins (clinical, genomic, phenotypic, imaging, metabolomic).
BIOMET's academic activity is complemented by the business activity carried by CRIBIOM
dedicated to providing services to its private partners, in particular metabolomics.
CRIBIOM is also a platform attached to the STAR Carnot Institute
BIOMET is equipped with 1 low resolution Agilent GCMS, 1 LCMS QTOF microTOFQBruker, 1 LCMS QExactive + Thermo, and has a GC FID for ultra-fast profiling of fatty acids.
Spectromètre de masse haute résolution couplé à la chromatographie liquide
Spectromètre de masse couplé à la chromatographie gazeuse
Martin, J.-C., Maillot, M., Mazerolles, G., Verdu, A., Lyan, B., Migne, C., Defoort, C., Canlet, C., Junot, C., Guillou, C., et al.(2015). Can we trust untargeted metabolomics? Results of the metabo-ring initiative, a large-scale, multi-instrument inter-laboratory study. Metabolomics11(4), 807-821.
Martin, J. C., Berton, A., Ginies, C., Bott, R., Scheercousse, P., Saddi, A., Gripois, D., Landrier, J. F., Dalemans, D., Alessi, M. C., et al.(2015). Multi-level systems biology modeling characterized the atheroprotective efficiencies of modified dairy fats in a hamster model. Am J PhysiolHeartCircPhysiol309, H935-H945.
Aidoud, N., Delplanque, B., Baudry, C., Garcia, C., Moyon, A., Balasse, L., Guillet, B., Antona, C., Darmaun, D., Fraser, K., et al.(2018). A combination of lipidomics, MS imaging, and PET scan imaging reveals differences in cerebral activity in rat pups according to the lipid quality of infant formulas. FASEB J32(9), 4776-4790.