Innovative Technologies to Investigate Atherosclerosis
The new multi-omics approaches enable us to gather a considerable amount of information, particularly in the field of cardiometabolic diseases. Technologies currently in full expansion include single-cell RNA sequencing and spatial transcriptomics and proteomics studies. However, it is always difficult, particularly with this type of approach, to import these new technologies into one’s laboratory, with questions such as the origin of the samples to be processed, whether they come from studies carried out on animals or humans, for example, and the sample preservation protocol, whether fresh, fixed or frozen. These are all questions that the experts we have invited to this webinar on new technologies in the study of cardiometabolic diseases will endeavor to answer. They will seek to highlight the advantages of one technology over another, what questions these technologies can answer, but also what questions they cannot answer, what their limitations are.
Dr.Benoit Pourcet & Pr. Bart Staels UMR1011 INSERM, Récepteurs Nucléaires – Maladies Métaboliques et Cardiovasculaires, Lille, France | Moderators |
Pr. Menno PJ de Winther. Dept. of Medical Biochemistry, Amsterdam University Medical Centers,University of Amsterdam, The Netherland | Cellular landscape in human and mouse atherosclerotic plaques: lessons about macrophages from single cell RNA sequencing analysis |
Pr Isabel Goncalves. Skåne University Hospital, Clinical Sciences Malmö, Lund University, Sweden | Using multiple omics to map human atherosclerotic plaque rupture signature |
Dr. Sikander Hayat. Department of Medicine 2, Medical Faculty, Aachen University, Germany | Spatial Systems Biology for reversing plaque phenotype using a novel Spatial human Atherosclerosis atlas |
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